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Metabolic syndrome

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What is metabolic syndrome?

Metabolic syndrome, also known as syndrome X or insulin resistance syndrome, is a collection of conditions that together increases the risk of developing heart disease or type 2 diabetes. These conditions include an increased waistline, hypertension (high blood pressure), increased blood sugar levels, high amounts of triglycerides and low levels of high density lipoprotein (HDL), also known as 'good' cholesterol, in the blood.

Metabolic syndrome is common in Australia, with around one in five people meeting the criteria for diagnosis [1] . Metabolic syndrome can affect both men and women and becomes more common as people get older.

Causes

The cause of metabolic syndrome is generally lifestyle related, including eating an unhealthy diet and lack of exercise. In some cases, genetic factors can also play a part.

Risk factors

Risk factors for metabolic syndrome include:

  • Being overweight or obese;
  • Being physically inactive;
  • Smoking;
  • Eating a diet high in sugar or saturated fat;
  • Older age;
  • Menopause, and;
  • Having a family history of metabolic syndrome or diabetes.

Limiting the amount of foods in your diet that contain saturated fat can help to prevent metabolic syndrome. 

Signs and symptoms

Obesity is the main obvious sign of metabolic syndrome. The other conditions generally do not show specific signs and symptoms, even when at dangerous levels. If you have consistently high blood sugar levels, you may experience an increase in thirst. Hypertension can cause dull headaches, dizzy spells or nosebleeds if it has reached a dangerously high level for an extended period of time.

Methods for diagnosis

Metabolic syndrome can be diagnosed by your doctor using a physical examination and blood tests to assess for each of the conditions that are associated with the disorder. A diagnosis is made if you are obese and any two of either a high blood sugar level, a high triglyceride level, hypertension or low HDL cholesterol level. Tests include:

A blood test can be used to check sugar and lipid levels in the blood. 

Types of treatment

Treatment of metabolic syndrome involves lifestyle changes to become healthier. These include:

In some cases, diet and lifestyle changes are not enough and medication may be required to lower blood pressure or reduce the amount of triglycerides in the blood. Your doctor will be able to recommend which medication is needed to treat the various features of metabolic syndrome.

Exercise can help to reduce the risk of, as well as treat, metabolic syndrome. 

Potential complications

The long-term complications of metabolic syndrome are heart disease and type 2 diabetes.

Heart disease

Heart disease, also known as cardiovascular disease, includes coronary artery disease, which is the formation of fat deposits inside the blood vessels of the heart. Heart disease can lead to angina, heart attack and death.

Type 2 diabetes

Type 2 diabetes is a chronic condition that affects the ability of your body to control the level of sugar in the blood. The condition can be effectively managed, but has complications including heart disease, nerve damage and kidney disease.

Prognosis

The outlook for people with metabolic syndrome is good if action is taken to address each feature of the syndrome to reach the recommended healthy targets.

Prevention

Metabolic syndrome is almost always preventable. Prevention involves maintaining a healthy weight, eating nutritious food, limiting fatty or sugar-filled foods and exercising regularly. It is also important to have regular health checks to monitor blood pressure, blood sugar and blood triglyceride levels. This will allow your doctor to identify any abnormal results and suggest a treatment plan to bring your results into a healthy range.

Eating a wide variety of healthy foods can help to prevent metabolic syndrome. 

References

  1. Harris, M.F. (2013) The metabolic syndrome. Australian Family Physician. 42:524-527 Accessed 14 November 2014, from link here

10 Most frequently asked questions (FAQs)

What is metabolic syndrome?
Metabolic syndrome, also known as syndrome X or insulin resistance syndrome, is a collection of conditions that together increase the risk of developing heart disease or type 2 diabetes. These conditions include a larger waistline, high blood pressure, increased blood sugar levels, high amounts of triglycerides and low levels of high density lipoprotein (HDL), also known as ‘good’ cholesterol, in the blood.
What are the symptoms of metabolic syndrome?
Obesity is the main sign of metabolic syndrome, while the other characteristics of metabolic syndrome generally do not show specific symptoms, even when at dangerous levels.
What causes metabolic syndrome?
The cause of metabolic syndrome is generally lifestyle-related, including eating an unhealthy diet and not getting enough exercise. In some cases, genetic factors can also play a part.
Who can develop metabolic syndrome?
Metabolic syndrome is common in Australia, with around one in five people meeting the criteria for diagnosis. Metabolic syndrome can affect both men and women and becomes more common as people get older.
How is metabolic syndrome diagnosed?
Your doctor can diagnose metabolic syndrome using a physical examination and blood tests to assess each of the characteristics associated with metabolic syndrome.
How is metabolic syndrome treated?
Treatment of metabolic syndrome involves lifestyle changes, which include regular exercise, eating healthily, limiting refined sugar and saturated fats, cutting down alcohol and quitting smoking.
Can metabolic syndrome be cured?
By making healthy lifestyle choices, metabolic syndrome can be cured.
What is the prognosis for people with metabolic syndrome?
The outlook for people with metabolic syndrome is good if action is taken to address each feature of the syndrome and to reach the recommended healthy targets.
What can be done at home to treat metabolic syndrome?
Regular exercise - a good goal is to do at least 30 minutes of exercise on most days of the week - will help treat metabolic syndrome.
Can metabolic syndrome be prevented?
Metabolic syndrome is almost always preventable. Prevention involves maintaining a healthy weight, eating nutritious food, limiting fatty or sugar-filled foods and exercising regularly. It is also important to have regular health checks to monitor blood pressure, and the levels of blood sugar and triglycerides (a type of fat found in the blood). This will allow your doctor to identify any abnormal results and suggest a treatment plan to bring your results into a healthy range.

Related topics

Diabetes insipidus

Diabetes insipidus (DI) is caused by a chemical imbalance that hinders the body’s ability to control its fluids. It can cause people to become very thirsty and pass large amounts of urine. If left untreated, the condition can cause life-threatening dehydration.

Type 1 diabetes

Type 1 diabetes is a long-term condition with impaired control of glucose (sugar) in the blood. It occurs when the pancreas cannot produce the hormone insulin, which normally controls the entry of glucose into cells. Individuals with type 1 diabetes need careful management, including insulin injections several times a day, or an insulin pump, to prevent complications.

Type 2 diabetes

Type 2 diabetes is a condition that affects the body’s ability to control blood sugar levels, and can lead to serious health problems. Although it is a lifelong condition, it can be effectively managed by controlling blood sugar levels, having regular check-ups and seeking early treatment for any complications.

Diabetic ketoacidosis

Diabetic ketoacidosis (DKA) is a life-threatening condition caused by a build-up of waste products called ketones in the blood. It occurs in people with diabetes when they have no – or very low levels of – insulin. DKA is most commonly seen in people with type 1 diabetes.

About this article

Title: Metabolic syndrome

Author: Dr Bow Tauro PhD, BSc (Hons)

First Published: 13 Jul 2015

Last reviewed: 17 Jan 2022

Category: Information on Metabolic syndrome

Average rating: 4.8 out of 5 (279 votes)

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