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Benign prostatic hyperplasia

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Fast facts

What is benign prostatic hyperplasia?

Benign prostatic hyperplasia (BPH), also known as prostatic hypertrophy, is an enlargement of the prostate gland. BPH can cause problems with urination (peeing). BPH happens to all men, to some degree, as they get older.

Causes

The cause of BPH is not completely understood, although hormones, such as testosterone, may play a role.

The prostate is a small ring-shaped gland that sits just under the bladder and in front of the rectum. It surrounds the urethra, the tube that carries urine from the bladder and through the penis. When it grows larger, the prostate gland can press on the bladder and the urethra, interfering with urination.

An enlarged prostate gland can interfere with normal urination. 

Risk factors

The factors that increase the risk of BPH are not very clear at this stage. Family history, increasing age, being overweight or obese, diabetes, high blood pressure (hypertension) and a diet high in saturated fat and red meat have been suggested.

Signs and symptoms

Symptoms of BPH can include:

These symptoms are sometimes known as lower urinary tract symptoms (LUTS).

Symptoms due to BPH often develop gradually and do not usually occur before 50 years of age. The increased size of the prostate does not always correspond to the level of symptoms you may experience.

Ruling out other conditions

Some serious conditions can cause similar symptoms to those of BPH. Checking in with your doctor if you have problems with urinating, or if your pattern of urination changes, can help to identify and treat these early on.

Blood in the urine is a symptom that can indicate serious health conditions that need prompt investigation.

Methods for diagnosis

Your doctor will ask you for details about your symptoms in order to understand how severe they are and how much they affect your lifestyle.

Your doctor may perform a digital rectal exam in order to examine the shape and size of the prostate gland. This test involves a doctor putting a gloved finger into the anus in order to examine the shape and size of your prostate gland.

Your doctor may recommend further tests or refer you to a specialist (urologist).

Protein-specific antigen testing

A blood test is used to to measure the level of prostate-specific antigen (PSA) in the blood. High PSA levels can be caused by a number of different prostate conditions including BPH, prostatitis (inflammation of the prostate) and prostate cancer.

There have been questions raised about PSA testing because PSA levels do not always reflect the risk of prostate cancer. Some men with high PSA levels do not have prostate cancer, while other men with relatively low PSA levels may have prostate cancer.

It is important to note that prostate cancer rarely causes lower urinary tract symptoms in its early stages, because it can grow within the prostate without pressing on the urethra.

Your doctor can explain more about PSA testing and discuss the potential benefits and harms of the test.

Additional tests

Other tests that may be recommended include:

Types of treatment

Men with mild BPH may not require treatment if the symptoms do not bother them. Symptoms can sometimes improve without treatment.

A variety of treatments and self-care measures are available:

Lifestyle changes

There are things you can do that can help to reduce and/or manage symptoms caused by BPH:

Bladder training

Bladder training involves exercises that can help to increase the amount of urine your bladder can hold before needing to urinate. Bladder training is not suitable for everyone; your doctor or urologist can advise whether it can help you.

Medications

Several types of medications can help you with the urinary flow problems that BPH causes. Once you start taking medications, you will need to continue to take them on an ongoing basis for them to be effective.

Medications include:

Alpha blockers

Alpha blockers such as prazosin and tamsulosin can help to relax muscles in the bladder and prostate, and improve urinary flow. Side effects of these drugs can include dizziness, headaches and, particularly with tamsulosin, little or no sperm when you ejaculate. They can also cause problems if you have eye surgery while taking these medications.

5-alpha-reductase inhibitors

5-alpha-reductase inhibitors, such as dutasteride and finasteride, work by blocking the production of dihydrotestosterone (DHR). DHR is a hormone that stimulates growth of the prostate. Blocking DHR can reduce the size of the prostate gland and improve urinary symptoms.

These medications are usually only prescribed for men who have a particularly large prostate. It can take a few months for these medications to have a noticeable effect.

Common side effects of these medications can include a decreased sex drive, erectile dysfunction, and problems with ejaculation. These medications can also cause birth defects in babies if the father is taking them when the baby is conceived, or if broken or crushed tablets are handled by a pregnant woman.

Complementary medicine

Saw palmetto (also known as Serenoa repens) has been used to treat urinary symptoms associated with BPH. However, trials have not shown evidence that it is effective.

Surgery

For men with severe BPH symptoms, surgery to remove some or all of the prostate may be recommended.

Transurethral resection of the prostate (TURP)

A small instrument called a resectoscope is inserted into the urethra. The end of the instrument (a wire loop) is used to cut away excess tissue in the region where the prostate is pressing on the urethra.

This operation is done under anesthesia. You may spend one or more nights in hospital recovering.

Transurethral resection of the prostate. 

Transurethral incision of the prostate (TUIP)

The resectoscope is used to make one or two cuts in the bladder neck, the area where the bladder and prostate connect. This can help to open up the area and increase urinary flow.

Laser-based surgeries

Techniques such as photoselective vaporization of the prostate (PVP) and Holmium laser enucleation of the prostate (HoLEP) are similar to TURP, but use lasers to remove the prostate tissue. These techniques are less invasive than TURP and may offer some benefits, such as reduced recovery time.

Prostatectomy

Rarely, the whole prostate may be removed. It is not commonly performed for BPH, but may be recommended if the prostate is severely enlarged.

Potential complications

While BPH is unlikely to cause serious health conditions, it can sometimes lead to:

Complications of surgery

All surgeries to treat BPH can have complications. Before surgery, your urologist can discuss the potential benefits and drawbacks of the surgical techniques available, and which of them may be most suitable for you.

Complications can include:

Prognosis

BPH does not usually cause serious health problems for men, although the symptoms can be bothersome and affect your quality of life. Generally, symptoms slowly get worse without treatment. Treatments can help to deal with symptoms, but can have significant side effects.

Prevention

The lifestyle measures listed in the 'Types of treatment' section above can help to prevent or delay BPH.

10 Most frequently asked questions (FAQs)

What is benign prostatic hyperplasia (BPH)?
Benign prostatic hyperplasia (BPH) is an enlargement of the prostate gland that can cause problems with urination. BPH is not cancer and does not increase the risk of getting prostate cancer.
What are the symptoms of benign prostatic hyperplasia (BPH)?
Not all men with BPH have symptoms. When they do show up, symptoms of BPH include a range of problems with urinating, such as difficulty beginning to urinate, straining while urinating, and a weakened or interrupted stream. Often, men will have to get up several times at night to urinate.
What causes benign prostatic hyperplasia (BPH)?
Most men have some level of BPH as they get older. The cause is not clear, but it is thought that hormones such as testosterone may play a role.
Who gets benign prostatic hyperplasia (BPH)?
Symptoms from BPH are uncommon before the age of 50, and become more common as men get older.
How is benign prostatic hyperplasia (BPH) diagnosed?
Your doctor will ask about your symptoms and perform a physical exam including a digital rectal exam (DRE) to check the prostate gland. A blood test called PSA is commonly used to help assess BPH. More tests such as urinalysis, ultrasound and urodynamic testing may be recommended if necessary.
How is benign prostatic hyperplasia (BPH) treated?
BPH that causes no or mild symptoms may not require treatment. If symptoms are causing problems, lifestyle measures, bladder training, medications or surgery are options.
Will benign prostatic hyperplasia (BPH) clear on its own?
While symptoms may sometime improve, particularly with lifestyle measures such as exercising, losing weight and avoiding alcohol and caffeine, they will generally tend to slowly get worse if BPH are untreated.
What can be done at home to treat benign prostatic hyperplasia (BPH)?
Lifestyle measures that help to manage urinary symptoms can help to manage BPH. Avoiding alcohol and caffeine, and not drinking fluids for a couple of hours before bed can reduce the need to urinate frequently. Regular exercise and losing weight (if you are overweight) can also help.
Can benign prostatic hyperplasia (BPH) be prevented?
There is some evidence that a diet low in fat and red meat may help to prevent the development of BPH.
Is benign prostatic hyperplasia (BPH) serious?
BPH is not cancer and does not increase the risk of getting prostate cancer. It rarely causes serious health problems for men, but can cause symptoms that can have a major impact on their lifestyles.

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About this article

Title: Benign prostatic hyperplasia

Author: Kellie Heywood

First Published: 14 Oct 2014

Last reviewed: 17 Jan 2022

Category: Information on Benign prostatic hyperplasia

Average rating: 4.0 out of 5 (1556 votes)

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