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Listeriosis

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What is listeriosis?

Listeriosis is a condition caused by Listeria monocytogenes bacteria. These bacteria are widespread in nature and can be found in the soil, water and in many animals. People most often get infected with listeria after eating food that is contaminated with the bacteria.

Listeriosis is normally a mild condition that passes after a few days and has no lasting effect. However, it can lead to complications. In pregnant women, listeriosis can lead to premature birth, miscarriage or stillbirth. In addition, a pregnant woman can transfer the bacteria to her unborn baby.

Causes

Most listeriosis cases occur as a result of eating contaminated food. Listeria monocytogenes bacteria can contaminate raw or processed food, including:

Foods that can harbor Listeria bacteria include salami, raw fish, soft cheeses and pre-packaged foods. 

Listeria monocytogenes bacteria are widespread in nature and are often found when testing food. They can contaminate food at any point of the food supply chain, from the soil in farms, through to all stages of food storage and processing, and in kitchens where food is prepared. Listeria are also unusual among bacteria, in that they can grow in refrigerated food.

Listeriosis often appears as outbreaks, due to an infected food source shared by multiple people. Listeriosis outbreaks occur more often in developed countries. They are rare events, appearing in 1 to 10 people per million, but severe listeriosis has a high death rate of one in five people. [1]

The incubation period of listeriosis, which is the time between infection and the appearance of illness, is highly variable and can be very long. Thus, it is sometimes hard to trace back the infection to its source. Many animal species also harbor the bacteria, which can then develop into listeriosis, in some animals.

Risk factors

Anyone can be infected with listeria, but not all people experience problems. People at risk of developing listeriosis include:

  • Pregnant women;
  • Babies;
  • Elderly people, and;
  • People with weak immune systems, due to illness or medication.

Listeriosis in pregnancy

In pregnant women infected with Listeria, the unborn baby can also become infected, when the bacteria move across the placenta and into the unborn baby's bloodstream. About one in five pregnant women who have listeriosis are in real danger of experiencing premature birth, birth complications, miscarriage or stillbirth.

Unborn babies and infants who contract listeriosis are at increased risk of developing complications of listeriosis, especially meningitis (see below).

Signs and symptoms

Most people who are infected with listeria will not get ill, or will experience only mild symptoms. Symptoms can resemble those of the flu and may include:

Severe listeriosis

If the bacteria infect the nervous system or the blood, severe listeriosis can set in. Severe listeriosis is a serious condition and requires hospitalization.

Symptoms of severe listeriosis can include:

Listeriosis in infants

In infants, symptoms can include:

Methods for diagnosis

If listeriosis is suspected, your doctor may send off tissue samples (or often blood samples) to test for the presence of Listeria.

In cases of suspected listeriosis in pregnancy, samples from the amniotic fluid and the placenta may be taken.

If your doctor suspects that the bacteria may have spread to the nervous system, they may wish to sample the fluid around the spinal cord and brain, by performing a lumbar puncture. In some cases, a magnetic resonance imaging (MRI) scan of the brain is performed.

For people infected with the bacteria, who do not feel ill, further testing or treatment is usually not necessary.

Types of treatment

If treatment is necessary, your doctor will prescribe a course of antibiotic medication, such as amoxicillin or ampicillin.

Potential complications

Listeriosis can cause the following complications:

Prognosis

Complications of listeriosis can result in serious, long-lasting harm and even death, particularly among infants who develop meningitis.

In healthy older children and adults, listeriosis usually passes after a few days with no lasting harm.

Prevention

The best way to prevent listeriosis is to practice good food-handling practices, including:

People at risk, such as pregnant women, may choose to avoid the risky foods listed above, including soft cheeses, unpasteurized dairy products, pâtés, deli meats, raw fish and other seafood.

References

  1. Claiborn K. (2011) Update on the listeriosis outbreak. The Journal of Clinical Investigation 121:4569.
  2. CDC - Listeria - Home. Accessed 22 July 2014 from link here
  3. Choices N.H.S. (2013 November 12). Listeriosis - NHS Choices. Accessed 22 July 2014 from link here
  4. Citro S. & Chiocca S. (2010). Listeria monocytogenes: a bacterial pathogen to hit on the SUMO pathway. Cell Research 20: 738740.
  5. Claiborn K. (2011). Update on the listeriosis outbreak. Journal of Clinical Investigation 121: 4569.
  6. Food poisoning (food-borne illness). Accessed 22 July 2014 from link here
  7. Listeriosis - Blue Book - Department of Health Victoria Australia. instructional. Accessed 22 July 2014 from link here
  8. Listeriosis (pathology). Encyclopedia Britannica. Accessed 22 July 2014 from link here
  9. Mateus T. Silva J. Maia R.L. et al. (2013). Listeriosis during Pregnancy: A Public Health Concern. ISRN Obstetrics and Gynecology 2013. Accessed from link here
  10. Murtagh J. MD. (2011). John Murtaghs General Practice (5th Revised edition.). North Ryde N.S.W.: McGraw-Hill Medical Publishing.
  11. Nandini Shetty Julian W Tang Julie Andrews. (2009). Infectious Disease: Pathogenesis Prevention and Case Studies (1st ed.). Wiley-Blackwell.
  12. Posfay-Barbe K.M. & Wald E.R. (2009). Listeriosis. Seminars in Fetal and Neonatal Medicine 14: 228233.
  13. Treatment prognosis and prevention of Listeria monocytogenes infection. Accessed 22 July 2014 from link here
  14. WHO | Listeriosis. WHO. Accessed 22 July 2014 from link here

10 Most frequently asked questions (FAQs)

What is listeriosis?
Listeriosis is a condition caused by Listeria monocytogenes bacteria. These bacteria are widespread in nature and can be found in the soil, water and in many animals. People most often get infected with Listeria after eating food that is contaminated with the bacteria.
What are the symptoms of listeriosis?
Symptoms of listeriosis resemble those of the flu and may include fever, chills, headache, feeling unwell, muscle pain and diarrhea. If the bacteria infect the nervous system or the blood, severe listeriosis can set in. Symptoms of severe listeriosis include stiff neck muscles, twitching, seizures, loss of physical coordination and confusion. In infants, symptoms can include loss of appetite or food refusal, jaundice, trouble breathing, shock, irritability, lack of energy, skin rash, and an upset stomach or vomiting.
How is listeriosis diagnosed?
Listeriosis is diagnosed by laboratory testing of tissue samples and blood.
How is listeriosis treated?
Listeriosis can be treated with a course of antibiotics.
Can listeriosis be cured?
Listeriosis is a curable disease, if treated quickly and correctly.
Will listeriosis clear on its own?
Most cases of listeriosis will clear after a few days. Complicated listeriosis in high-risk people requires medical attention.
Is listeriosis contagious?
Listeriosis does not pass from person to person.
How is listeriosis spread?
Listeriosis is spread via contaminated food. A pregnant woman can transmit the bacteria to her unborn baby.
Can listeriosis be prevented?
Although the chance of infection cannot be completely eliminated, listeriosis can be avoided by practicing good food-handling practices. People at risk can avoid risky foods.
What happens if listeriosis occurs during pregnancy?
About one in five pregnant women who have listeriosis are in real danger of experiencing premature birth, birth complications, miscarriage or stillbirth. Unborn babies and infants who contract listeriosis from their mother in the womb are at increased risk of developing complications of listeriosis.

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About this article

Title: Listeriosis

Author: Dr Idan Ben-Barak PhD, MSc, BSc (Med)

First Published: 20 Oct 2014

Last reviewed: 17 Jan 2022

Category: Information on Listeriosis

Average rating: 4.7 out of 5 (1554 votes)

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