MERS
What is Middle East respiratory syndrome?
Middle East respiratory syndrome (MERS) is an emerging infectious disease of the airways and lungs. It first appeared in April 2012 in Saudi Arabia. Most cases have occurred in Saudi Arabia and nearby countries, but the virus has also spread to some European and Asia-Pacific countries, as well as to the US.
About 25-40% of people identified with the virus have died. As of June 2015, 1180 cases have been identified; at least 480 of these have died from complications of the disease. [1] [2] [3]
An outbreak of MERS in the Republic of Korea was first identified in May 2015 and is ongoing at time of writing. The virus was passed on from an infected man returning from the Middle East to others at a hospital he was being treated at. As of June 5 2015, 30 cases have been identified in the Republic of Korea and two people have died. [1]
As this is a new disease, and information on it is still being collected and analyzed, many aspects of MERS are still not completely known; what we know of MERS at present may change significantly as the virus is studied and more clinical cases emerge.
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Virus
A microscopic infectious agent that replicates itself only within cells of living hosts; a piece of nucleic acid (DNA or RNA) wrapped in a protein coat.
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Respiratory
Relating to respiration, the process of inhaling and exhaling air.
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WHO | Middle East respiratory syndrome coronavirus (MERS-CoV) – Republic of Korea. WHO. Accessed 5 June 2015, from
External link
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Middle East respiratory syndrome - The Lancet. Accessed 5 June 2015, from
External link
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Spread of MERS to South Korea and China - The Lancet Respiratory Medicine. Accessed 5 June 2015, from
External link
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WHO | Middle East respiratory syndrome coronavirus (MERS-CoV) – Republic of Korea. WHO. Accessed 5 June 2015, from
External link
Causes
The cause of MERS has been identified as a new type of virus belonging to the coronavirus family. The virus most likely originated in an animal, such as a camel or bat, and 'made the jump' from animal to human.
It is not yet clear exactly how the MERS virus spreads. The virus can be transmitted from animal to human. It is also capable of being transmitted from human to human, but not very efficiently. Thus, the risk of catching MERS from an infected person is currently thought to be not very high. It is known to be transmitted during close contact between people; for example, to health workers caring for people with the virus.
The most likely form of virus transmission is droplet transmission. When a person infected with MERS sneezes or coughs, millions of tiny droplets, each containing many viruses, are spread into the air. If a droplet enters your nose or mouth, you may then become infected with the virus. The droplets can also collect on surfaces and objects; you can then catch the virus by touching an infected surface and then touching your nose or mouth area.
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Virus
A microscopic infectious agent that replicates itself only within cells of living hosts; a piece of nucleic acid (DNA or RNA) wrapped in a protein coat.
Risk factors
People at increased risk of contracting MERS include:
- People living or travelling in the Arabian Peninsula;
- People in close contact with a person who has a confirmed case of MERS;
- Healthcare workers in areas where MERS occurs, and;
- People in close contact with a traveler returning from the Arabian Peninsula who has shown signs of a respiratory infection.
People who have current or significant previous health problems are more likely to develop MERS symptoms, to develop serious illness and to die of the illness.
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Respiratory
Relating to respiration, the process of inhaling and exhaling air.
Signs and symptoms
People who are infected with the MERS virus, especially if they were previously healthy, can sometimes exhibit no symptoms at all, or only mild symptoms.
The most common signs and symptoms of a MERS infection are:
- Fever, chills;
- Coughing, and;
- Shortness of breath.
Other less common symptoms that have been observed are:
- Diarrhea;
- Sore throat;
- Coughing up of blood;
- Vomiting;
- Abdominal pain, and;
- Headache.
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Virus
A microscopic infectious agent that replicates itself only within cells of living hosts; a piece of nucleic acid (DNA or RNA) wrapped in a protein coat.
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Abdominal
Relating to the abdomen, the middle portion of the trunk which contains organs such as the intestines, stomach and liver.
Methods for diagnosis
A doctor will give a tentative diagnosis of MERS based on the person's clinical symptoms and their history (such as travel or any contact with infected people). A definite diagnosis relies on laboratory tests to analyze the virus.
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Virus
A microscopic infectious agent that replicates itself only within cells of living hosts; a piece of nucleic acid (DNA or RNA) wrapped in a protein coat.
Types of treatment
There is currently no specific treatment for MERS. Rather, the treatment is supportive and focuses on managing the symptoms that appear.
Potential complications
People with MERS can develop complications including severe pneumonia and kidney failure. These complications can lead to serious illness and death.
Prevention
Steps you can take to prevent infection with the MERS virus are similar to those of other viral diseases transmitted by sneezing and coughing. These can include:
- Cleaning and disinfecting surfaces and objects that might be infected;
- Avoiding close contact with infected people, and;
- Avoiding touching the mouth, eyes and nose areas of the face.
In addition, MERS appears to pass from infected animals to humans. As the virus has been identified in camels, avoiding contact with camels and camel products (raw milk, urine, uncooked camel meat) may help prevent infection.
There is currently no vaccine for MERS.
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Virus
A microscopic infectious agent that replicates itself only within cells of living hosts; a piece of nucleic acid (DNA or RNA) wrapped in a protein coat.
References
- WHO | Middle East respiratory syndrome coronavirus (MERS-CoV) – Republic of Korea. WHO. Accessed 5 June 2015, from link here
- Middle East respiratory syndrome - The Lancet. Accessed 5 June 2015, from link here
- Spread of MERS to South Korea and China - The Lancet Respiratory Medicine. Accessed 5 June 2015, from link here
- CDC - Coronavirus - Middle East Respiratory Syndrome - MERS-CoV. Accessed 10 July 2014 from link here
- CDCMERS-Photos. Accessed 10 July 2014 from link here
- Choices N.H.S. (2014 September 7). Camels may be source of MERS virus transmission - Health News - NHS Choices. Accessed 10 July 2014 from link here
- Health c=AU; st=Victoria; o=State G. of V. ou1=Department of. Update: Middle East Respiratory Syndrome Coronavirus (MERS-CoV) - 13 January 2014: Chief Health Officer - Department of Health Victoria Australia. guidelines. Accessed 10 July 2014 from link here
- Infographic: MERS Health Advisory | Travelers Health | CDC. Accessed 10 July 2014 from link here
- MERS virus weakened by mutations researchers found - News - Nature Middle East. Accessed 10 July 2014 from link here
- Michael T. Madigan John M. Martinko Kelly S. Bender Daniel H. Buckley David A. Stahl. Brock Biology of Microorganisms (14th ed.). Benjamin Cummins. Accessed from link here
- MERS_CoV_Update_09_May_2014.docx - MERS_CoV_Update_09_May_2014.pdf. Accessed 10 July 2014 from link here
- Middle East Respiratory Syndrome (MERS) Research NIAID NIH. Accessed 10 July 2014 from link here
- Middle East respiratory syndrome coronavirus. Accessed 10 July 2014 from link here
- Present danger. (2014). Nature 510: 311311.
- WHO | Frequently Asked Questions on Middle East Respiratory Syndrome Coronavirus (MERS?CoV). WHO. Accessed 10 July 2014 from link here
- WHO | Middle East respiratory syndrome coronavirus (MERS-CoV) update. WHO. Accessed 19 June 2014 from link here
10 Most frequently asked questions (FAQs)
Middle Eastern Respiratory Syndrome (MERS) is an emerging viral infectious disease of the airways and lungs. What are the symptoms of MERS? People who are infected with the MERS virus, especially if they were previously healthy, can sometimes exhibit no symptoms at all or only mild symptoms. The most common signs and symptoms of a MERS infection are fever, chills, coughing and shortness of breath. The cause of MERS has been identified as a new kind of virus, which belongs to the coronavirus family. The virus is currently found almost exclusively among people who live in the Arabian Peninsula, or who have travelled there or been in close contact with infected people. A doctor may give a tentative diagnosis of MERS based on the person's clinical symptoms and their history (travel, contact with infected people, etc.). A definite diagnosis relies on laboratory tests to analyze the virus. There is currently no specific treatment for MERS. Treatment is supportive and focuses on managing the symptoms that appear. MERS appears to pass from camels to humans and between people who are at close contact such as family members or healthcare personnel treating MERS patients. Steps you can take to prevent infection with the MERS virus are similar to those of other viral diseases transmitted by sneezing and coughing. In addition, MERS appears to pass from infected animals to humans. As the virus has been identified in camels, avoiding contact with camels and camel products (untreated milk, urine, uncooked camel meat) may help prevent infection. There is currently no vaccine for MERS. MERS is a serious condition with significant rates of complications and death.
Related topics
Novel coronavirus (COVID-19)
Coronaviruses are type of virus. They are many kinds and can make humans and animals sick. Some coronaviruses can cause illness similar to the common cold and others can cause more serious diseases, including Severe Acute Respiratory Syndrome (SARS) and Middle East respiratory syndrome (MERS). A new strain of the coronavirus identified in Wuhan City in China in December 2019 was named SARS-CoV-2. SARS is a highly infectious respiratory viral disease, which presents much like flu (fever, sore throat, dry cough, headache, chills, stiff muscles). Quarantining of patients is the only option, however there have been no reported cases of SARS since 2004. A common cold is a viral infection of the upper respiratory tract. Symptoms include a stuffy or runny nose, coughing and sneezing. They are not usually serious and will generally get better by themselves within a few days to a week. The flu, or influenza, is a common viral infection, which causes fevers, headache, coughing and muscle aches. It is different to the common cold, which usually has relatively milder symptoms. Rarely, complications can occur with the elderly, children and people with weakened immune systems.