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Heartburn

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What is heartburn?

Heartburn, also known as gastro-esophageal reflux disease (GORD) or indigestion, is a very common condition in which the stomach contents and/or acid are able to move back upward into the esophagus, and occasionally back into the mouth.

An estimated 15-20% of people experience an episode of heartburn at least once a week, with all age groups affected. [1] Most people can manage their symptoms with antacid tablets and avoiding trigger factors, but some chronic (ongoing) cases will require treatment.

Causes

When food is eaten, it travels from the mouth, through the esophagus to the stomach. The esophagus is a muscular tube, which is part of the digestive system and uses rhythmic muscular movements (peristalsis), along with gravity, to move food downwards.

Just before the food reaches your stomach, it must pass through a small band of muscles called your lower esophageal sphincter. When you eat, your esophageal sphincter relaxes and lets food pass through, down into your stomach and then closes again - much like a valve. During heartburn, the esophageal sphincter does not work properly, allowing stomach contents and/or acid to rise upwards, irritating the esophagus. In some cases, the stomach content and acid can travel up all the way to the back of the mouth.

A closed and open lower esophageal sphincter. 

Risk factors

Risk factors for heartburn include:

Hiatus hernia

A hiatus hernia is a condition in which part of your esophagus or stomach bulges into your chest cavity, through a gap in your diaphragm called your hiatus. This distorts the anatomy and can affect the lower esophageal sphincter, contributing to heartburn. This condition typically develops gradually over time, in adults. Heartburn may be the only symptom of a hiatus hernia.

Obesity and age

Being overweight or obese (obesity) puts extra pressure on your esophageal sphincter, making it easier for acid reflux to occur. You are also more likely to experience heartburn as you get older.

Pregnancy

Being pregnant can put a great deal of pressure on your digestive system, especially as you reach the final few months. Your growing womb pushes your stomach upwards and your esophageal sphincter relaxes, allowing acid reflux to occur.

Diet

You may find that certain fatty or spicy foods, chocolate, coffee and other caffeinated drinks, tomato products, peppermint, hot drinks and also alcohol may cause symptoms.

Smoking

The chemicals released when you smoke relax your esophageal sphincter, making heartburn more likely.

Medications

Taking certain medications can make your heartburn symptoms worse either by relaxing your esophageal sphincter or irritating your esophagus. The most commonly implicated drugs are:

  • Non-steroidal anti-inflammatory pain-relief drugs (NSAIDs), such as ibuprofen or aspirin;
  • Calcium-channel blockers - these are prescribed to help with blood pressure, circulation and heart problems;
  • Corticosteroids - these are given when you are have inflammatory conditions or autoimmune reactions;
  • Selective serotonin reuptake inhibitors (SSRIs) - these are commonly prescribed antidepressants;
  • Bisphosphonates - these are used to improve bone strength in conditions, such as osteoporosis, and;
  • Nitrates - these are a group of medicines that relax and dilate your blood vessels.

Signs and symptoms

Heartburn

This is an uncomfortable burning sensation, or pain, felt behind your breastbone (sternum) and lower chest usually after you have eaten. Lying down or leaning forwards makes it worse. The pain can often worsen late at night some hours after eating as lying down allows acid to reflux into the esophagus.

Acid reflux

You may experience an acidic, unpleasant taste in your mouth or throat caused by stomach acid refluxing back into your esophagus. Sometimes you may regurgitate small amounts of undigested food and liquids back into your mouth.

Nausea

You may feel sick, especially after eating, smoking, drinking or lying down soon after a meal.

Excess saliva

This is also called water brash and is a common symptom of heartburn, due to the fact that saliva neutralizes regurgitated stomach acid.

Belching

You may find yourself constantly belching, often with an acidic aftertaste. Your abdomen may also feel bloated and uncomfortable.

Coughing and hoarseness

You may develop a cough at night, or when you lie down, and feel as though you are having difficulty breathing. If you already have asthma, heartburn can irritate your airways and make symptoms worse. You may find your voice becomes hoarse or you get constant laryngitis (inflammation of your voice box).

Pain or difficulty swallowing.

You may experience pain (odynophagia) or difficulty swallowing (dysphagia). You might also feel as if something is stuck in your throat or behind your breastbone. These symptoms should be mentioned to your doctor as they can also be signs of other conditions.

Tooth decay

In long-term cases, acid reflux can damage your tooth enamel and cause tooth decay.

Symptoms in babies or small children

Heartburn can occur in young children, as their esophagus is much shorter than an adults, which means it is easier for their stomach contents to be regurgitated (brought up). If your child often brings up food, cries while arching their back and is irritable after feeding, heartburn may be the cause. These symptoms can be caused by other conditions, so it is important to seek advice from your doctor if you are concerned. Keeping your child's head higher than the level of their stomach during feeding and afterwards may reduce the incidence of reflux.

Seek medical attention if these symptoms appear

Methods for diagnosis

Your doctor can usually suspect heartburn by asking about your symptoms and taking a full medical history. Further testing may be required, such as:

Gastroscopy

Gastroscopy uses a thin, flexible tube containing a camera and light to view the internal lining of the esophagus, stomach and parts of the small intestine. You will usually be given light sedation to make you relax during the procedure. Often, you will be asked to fast for 12 hours prior to the test. Gastroscopy can accurately provide a detailed view of the esophagus and exclude other causes for the symptoms.

Manometry

An esophageal manometry is a test designed to discover if your esophageal sphincter is functioning properly. It involves a tube being inserted through your nose into your esophagus and down into your stomach to measure the pressure of your esophageal contractions. It is usually only done in cases where surgery is being considered.

Barium swallow

A barium swallow is a procedure in which you swallow a radioactive substance that will show up on an X-ray. This test is usually done to examine your pharynx and esophagus. It can assess the function of the esophageal sphincter.

24-hour pH monitoring

This procedure is usually only offered if you still have symptoms after a course of treatment and a gastroscopy hasn't revealed the cause. It will monitor whether acid reaches your esophagus during a 24-hour period. A thin tube, which is attached to a device measuring acid levels, is inserted through your nose into your esophagus and left there for 24 hours. You will be asked to record all your reflux symptoms in a diary during this time. An alternative form of this procedure involves attaching a similar device to your esophagus via endoscopy. This device transmits its readings and then is excreted with your stool.

Types of treatment

In the majority of heartburn cases, dietary and lifestyle changes, along with medication, are the mainstays of treatment. Your doctor may advise the following changes before prescribing you any medications:

Self care

Medications

There are numerous medications available for heartburn:

Surgery

Surgery is generally offered in severe cases of heartburn that haven't responded to lifestyle changes and other forms of treatment. Laparoscopic (keyhole) surgery is generally used to perform fundoplication, which is the gold-standard treatment. It involves wrapping the top of your stomach around the lower part of the esophagus to tighten up the esophageal sphincter. The surgery can be combined with other procedures, particularly treatment of a hiatus hernia, if present. Heartburn surgery is a major surgical procedure, which is performed under general anesthesia and involves several days in hospital. It carries the potential for severe complications, such as difficulty swallowing, damage to internal organs, and even failure of the procedure. Careful consideration and thorough discussion with your surgeon are recommended before embarking on any surgery.

Potential complications

While the majority of cases tend to improve with lifestyle changes and medications, if not adequately treated, heartburn can lead to damage to the lining of the esophagus. The lining of the esophagus is not designed to cope with persistent exposure to stomach acid, so it can lead to the following conditions:

Esophageal ulcers

You may develop ulcers in your esophagus, due to constant irritation from acid. These can cause pain, bleeding and make swallowing uncomfortable. Sometimes these ulcers can bleed, but you may not realize it, as it can be subtle, or lead to dark stools (rather than the typical blood stained stools). A simple stool test can detect the presence of any unseen blood in your stool. Antacids can be taken to reduce your stomach acid and alginates can be taken to relieve the symptoms.

Barrett's esophagus

Barrett's esophagus only occurs after repeated bouts of acid reflux, which change the type of cells that grow in your lower esophagus. It is more common if you are between 50-70 years of age. This condition carries a higher risk for esophageal cancer, but your doctor can arrange regular monitoring to help prevent this.

Esophageal cancer

This is heavily linked to Barrett's esophagus. If caught early enough, this type of cancer can usually be treated.

If you have the following, you have a higher risk of developing esophageal cancer:

Stricture

After repeated exposure to stomach acid, your esophagus can become form scar tissue. This can cause stricture, or narrowing of the esophagus, making it difficult for food to pass down to the stomach. Typical symptoms include difficulty swallowing, regurgitation and heartburn.

Throat and lung problems

Repeated episodes of heartburn can leave your throat feeling hoarse and irritate your vocal cords. If stomach acid is inhaled into your lungs, it can cause aspiration pneumonia and symptoms similar to asthma. If acid continues to enter the lungs, it can cause damage resulting in permanent complications, such as bronchiectasis or pulmonary fibrosis.

Prognosis

Many cases of heartburn respond well to lifestyle changes and medications. If you experience recurrent heartburn, it is important to talk to your doctor, rather than simply endure the symptoms.

Prevention

Maintaining a healthy body weight, not smoking, and avoiding pressure on the abdomen, such as wearing tight clothing or leaning over soon after eating, may help to prevent heartburn.

References

  1. Gastro-oesophageal reflux disease. GESA - Gastroenterological Society of Australia. Accessed 22 July 2014 from link here
  2. Reflux Surgery London | Anti Reflux Laparoscopic Surgery London. Accessed 22 July 2014 from link here
  3. Acid reflux (gastroesophageal reflux disease) in adults. Accessed 20 July 2014 from link here
  4. Diagnosing GORD in Respiratory Medicine. Accessed 20 July 2014 from link here
  5. GESA - Gastroenterological Society of Australia. Accessed 22 July 2014 from link here
  6. Health direct. Accessed 18 July 2014 from link here
  7. Heartburn and Gastro-oesophageal reflux disease - NHS Choices. Accessed 21 July 2014 from link here
  8. RACGP - GORD. Accessed 18 July 2014 from link here
  9. Reflux Surgery London | Anti Reflux Laparoscopic Surgery London. Accessed 22 July 2014 from link here
  10. Reflux_Disease.pdf. Accessed 22 July 2014 from link here
  11. Treatment Challenges in the Management of Gastroparesis-Related GERD. Accessed 22 July 2014 from link here

10 Most frequently asked questions (FAQs)

What is heartburn?
Heartburn, also known as gastro-esophageal reflux disease (GORD) or indigestion, is a very common condition in which the stomach contents and/or acid are able to move back upward into the esophagus, and occasionally back into the mouth.
What are the symptoms of heartburn?
The most common symptoms of heartburn are a burning sensation in the throat, a bad acidic taste in the mouth, belching, chest pain, excess saliva and sometimes coughing or hoarseness. Sometimes you can get acid reflux in your mouth, which might make you feel sick.
What causes heartburn?
Heartburn is caused when your lower esophageal sphincter (LOS) lets stomach acid flow back upwards into your esophagus. The LOS is similar to a valve; during heartburn it either does not work properly or is too relaxed, allowing stomach contents out instead of keeping them in.
Who develops heartburn?
Anyone can develop heartburn, but it is more common in men and people over 50 years of age. It is also common in young children, as their shorter esophagus makes it easier for stomach contents to get regurgitated.
Is heartburn serious?
In most cases heartburn is not serious and simply causes discomfort and annoyance. In long-term cases though, the continuous acid reflux can damage the lining of your esophagus. If you have heartburn for more than 10 years, it may put you at higher risk of esophageal cancer.
How is heartburn treated?
Most cases of heartburn can be treated with lifestyle changes and medication. Surgery is mainly offered for severe heartburn, or if you have a hiatus hernia.
What can be done at home to treat heartburn?
Eating smaller, regular meals, rather than large servings, particularly before bedtime, may help treat and prevent heartburn. Avoiding foods such as coffee, chocolate, fatty or spicy foods, and alcohol, especially with meals, may also be helpful. Avoid smoking, stress and eating quickly. Raising the head of your bed by placing blocks of wood under the legs of the bed will lessen reflux by keeping your head at a higher level than your stomach.
How common is heartburn?
Heartburn is very common, with an estimated one in five people experiencing it on a weekly basis. One in 10 people are thought to experience an episode every day.
What can make heartburn worse?
Heartburn is made worse by eating late at night, with alcohol, in a hurry or when stressed. Lying down or leaning over soon after eating also makes heartburn worse.
Will heartburn return?
In many cases, heartburn tends to return. However, adhering to lifestyle changes and medications can make this less likely.

Related topics

Barrett’s esophagus

Barrett's oesophagus occurs when the cells lining the oesophagus – the tube that connects the mouth and the stomach – change from a type of cell called squamous into columnar (cells more typical of the stomach and small intestine), due to damage from acid reflux.

Gastritis

Gastritis describes a group of conditions characterised by inflammation of the stomach lining. It occasionally causes symptoms like reduced hunger, nausea and indigestion, but in most cases doesn't produce symptoms at all. Gastritis usually isn’t dangerous and generally improves with treatment.

Chest pain

Chest pain has many causes, ranging from muscle strain to more serious cardiovascular problems such as heart attack. If you do experience chest pain, it is important to seek prompt medical attention.

Hernia

A hernia occurs when an internal organ pushes through a weakness in the abdominal wall, often as a result of increased internal pressure from straining or heavy lifting. This creates a bulge on the abdomen that can be felt through the skin.

About this article

Title: Heartburn

Author: Karen McCloskey BHSc

First Published: 23 Sep 2014

Last reviewed: 17 Jan 2022

Category: Information on Heartburn

Average rating: 4.7 out of 5 (1554 votes)

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