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Transient ischaemic attack (TIA)

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What is a transient ischaemic attack?

A transient ischemic attack (TIA) is a temporary neurological episode. It is also known as a 'mini-stroke'. It is caused by a temporary blockage or narrowing in a blood vessel leading to the brain. A person experiencing TIA will have signs and symptoms like those of a stroke, but will recover completely within minutes or a few hours.

TIA's main significance is as a warning sign: TIAs occur when the blood vessels feeding the brain are not in good condition. A person who has had a TIA is at serious risk of stroke, often within days of the TIA.

Signs and symptoms

The signs and symptoms of a TIA are like those of a stroke. The difference between TIA and stroke is that in a TIA signs and symptoms are completely resolved, usually within a few minutes, while a stroke's effects are permanent. Thus, it is impossible - and inadvisable - to try and tell a TIA from a stroke while it is occurring.

Early warning signs - FAST

The FAST test is a set of early warning signs for stroke that anyone can use to recognize stroke. FAST is an acronym used to remember these points:

The FAST test is used to diagnose early warning signs of a stroke.  

Additional TIA signs and symptoms

Symptoms of a TIA include:

TIA and migraine

The early signs of a stroke can sometimes be similar to those of migraine. An authoritative diagnosis can only be made with a brain scan. For people who suffer from migraines, it is important to notice irregularities in their migraine symptoms and be alert to the possibility of stroke. An attack that is much more sudden than usual, and/or has different visual symptoms, might not be a migraine attack, but an early sign of stroke.

Causes and types

A TIA is caused by a temporary blockage or narrowing in a blood vessel leading to the brain. Loss of blood supply to an area of the brain will cause a temporary problem within that area. In a TIA, the blood clot normally dissolves after a few minutes, and normal blood flow to the brain area is resumed.

A TIA can be the result of:

A transient ischaemic attack is normally caused by a temporary blockage of a brain artery. 

Risk factors

Risk factors for TIA are similar to those of stroke, and include:

  • High blood pressure;
  • Age - anyone can have a TIA, but the risk increases in older adults;
  • Smoking;
  • A poor diet, obesity, high cholesterol;
  • Diabetes;
  • A sedentary lifestyle;
  • Stress and depression;
  • A family history of stroke;
  • Ethnicity - the chance of stroke is higher in some populations;
  • Excessive alcohol consumption;
  • Heart disease, such as atrial fibrillation, and;
  • A recent TIA or a previous stroke.

Methods for diagnosis

Since a TIA is sudden and is over quickly, diagnosis of a TIA typically happens after it has passed. Your doctor will ask you about your medical history and status, and about the symptoms you have experienced. Your doctor may then have you undergo a brain scan (a CT scan or an MRI) to understand why the TIA occurred and check for the risk of a future stroke. Blood tests can also help with diagnosis.

Your heart activity may also be examined and monitored, as stroke events can be closely related to heartbeat abnormalities.

Types of treatment

TIA in itself is not treated, as it is a temporary event and leaves no lasting damage. After a TIA, the focus will be on monitoring you for signs of a stroke and preventing a stroke from occurring. This may include medication (for example, drugs to lower blood pressure) and lifestyle change (such as quitting smoking). Surgery is also an option in some cases.

The specific treatment after a TIA depends on underlying risk factors.

Prognosis

A TIA in itself is thought to leave no lasting damage, and its main significance is as a warning sign. However, some recent research suggests that TIAs can cause minor brain injury. [2] These may not affect the person in a noticeable way, but if TIAs recur, they may have a cumulative effect on brain health.

Prevention

You can lower your chances of a TIA (or the chances of further TIAs and a stroke) by adopting a healthier lifestyle; by limiting your alcohol consumption, quitting smoking, exercising and eating healthier food.

References

  1. Murtagh, J. (2008). John Murtagh’s Patient Education (Australian edition.). North Ryde, N.S.W.: McGraw-Hill Book Company Australia.
  2. Edwards, J.D., Meehan, S.K., Levy, A.R., et al. (2011). Changes in Intracortical Excitability After Transient Ischemic Attack Are Associated With ABCD2 Score. Stroke 42: 728–733.
  3. (Victoria) Department of Health. Stroke. Accessed 5 August 2014 from link here
  4. Edwards J.D. Meehan S.K. Levy A.R. et al. (2011). Changes in Intracortical Excitability After Transient Ischemic Attack Are Associated With ABCD2 Score. Stroke 42: 728–733.
  5. Van der Worp H.B. & van Gijn J. (2007). Acute Ischemic Stroke. New England Journal of Medicine 357: 572–579.
  6. Broderick J.P. Palesch Y.Y. Demchuk A.M. et al. (2013). Endovascular Therapy after Intravenous t-PA versus t-PA Alone for Stroke. New England Journal of Medicine 368: 893–903.
  7. Ciccone A. Valvassori L. Nichelatti M. et al. (2013). Endovascular Treatment for Acute Ischemic Stroke. New England Journal of Medicine 368: 904–913.
  8. Ding D. (2014). Intravenous Versus Intra-arterial Thrombolysis for Acute Ischemic Stroke Secondary to Basilar Artery Occlusion. Journal of Cerebrovascular and Endovascular Neurosurgery 16: 39–41.
  9. Donnan G.A. Fisher M. Macleod M. et al. (2008). Stroke. The Lancet 371: 1612–1623.
  10. Gibson C.L. (2013). Cerebral ischemic stroke: is gender important? Journal of Cerebral Blood Flow & Metabolism 33: 1355–1361.
  11. Grip O. Kuoppala M. Acosta S. et al. (2014). Outcome and complications after intra-arterial thrombolysis for lower limb ischaemia with or without continuous heparin infusion. British Journal of Surgery 101: 1105–1112.
  12. O’Donnell M.J. Xavier D. Liu L. et al. (2010). Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. The Lancet 376: 112–123.
  13. Stroke. Better Health Channel. Accessed 5 August 2014 from link here
  14. Stroke Information | cdc.gov. Accessed 5 August 2014 from link here
  15. Stroke Information Page: National Institute of Neurological Disorders and Stroke (NINDS). Accessed 5 August 2014 from link here
  16. Stroke symptoms and diagnosis. Accessed 5 August 2014 from link here
  17. Transient ischemic attack. Accessed 5 August 2014 from link here
  18. Van der Worp H.B. & van Gijn J. (2007). Acute Ischemic Stroke. New England Journal of Medicine 357: 572–579.
  19. What Is a Stroke? - NHLBI NIH. Accessed 5 August 2014 from link here
  20. WHO | Stroke Cerebrovascular accident. WHO. Accessed 5 August 2014 from link here

9 Most frequently asked questions (FAQs)

What is a transient ischemic attack?
A transient ischemic attack (TIA) is a temporary neurological episode also known as a 'mini-stroke'.
What causes a transient ischemic attack?
A TIA is caused by a temporary blockage or narrowing in a blood vessel leading to the brain.
What is the 'FAST' test for stroke?
The FAST test is a set of early warning signs for stroke that anyone can use to recognize a stroke. FAST is an acronym for: Face (is it droopy, flaccid, especially just on one side? Can the person smile?); Arms (can the person lift both their arms above their head?); Speech (are there problems speaking and/or understanding speech? Is speech slurred?), and; Time (quick action will improve the chances of survival and recovery).
What are the symptoms of a transient ischemic attack?
The signs and symptoms of a TIA are like those of a stroke. They can include: sudden weakness on one side of the body (hemiparesis); inability to move or lift the arm; sudden paralysis of one side of the body (hemiplegia); movement and coordination problems; cognitive problems such as confusion, difficulty with speech, understanding speech, formulating thoughts and memory loss; blurred vision, loss of vision, or seeing only half the regular vision field (hemianopia), or sudden blindness in one eye. The difference between a TIA and a stroke is that a TIA usually passes within minutes, causing little lasting damage, while a stroke's effects are permanent. Thus, it is neither possible nor advisable to try to tell a TIA from a stroke while it is occurring.
Who gets a transient ischemic attack?
While anyone can have a TIA, it is more common in older adults. High blood pressure, smoking, a poor diet and obesity are also major contributors to the risk of a TIA.
How is a transient ischemic attack diagnosed?
Since a TIA is sudden and is over quickly, diagnosis of a TIA typically happens after it has passed. Your doctor will ask you about your medical history and status, and about the symptoms you have experienced. Your doctor may then have you undergo a brain scan (a CT scan or an MRI) to understand why the TIA occurred and to check for the risk of a future stroke. Blood tests can also help with diagnosis.
How is a transient ischemic attack treated?
TIA in itself is not treated, as it is a temporary event and leaves no lasting damage. After a TIA, the focus will be on monitoring you for signs of a stroke and preventing a stroke from occurring. This may include medication (for example, drugs to lower blood pressure) and lifestyle change (such as quitting smoking). Surgery is also an option in some cases.
Can a transient ischemic attack be prevented?
The risk of a TIA cannot be completely eliminated, but you can lessen the chance of it happening by stopping smoking, reducing high blood pressure, becoming more physically active and improving your diet.
What is the outlook for a transient ischemic attack?
A TIA in itself is thought to leave no lasting damage, and its main significance is as a warning sign for future stroke.

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About this article

Title: Transient ischaemic attack (TIA)

Author: Dr Idan Ben-Barak PhD, MSc, BSc (Med)

First Published: 16 Jul 2015

Last reviewed: 17 Jan 2022

Category: Information on Transient ischaemic attack (TIA)

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